Journal: Journal of medicinal chemistry

Article Title: Synthesis and Evaluation of 1,2,4-Triazolo[1,5- a ]pyrimidines as Antibacterial Agents Against Enterococcus faecium

doi: 10.1021/jm501831g

Figure Lengend Snippet: Minimal-Inhibitory Concentrations (MICs, μ g/mL) of Compounds 1, 10, 13, 16, 83, 84, and Vancomycin with Additional E. faecium Strains

Article Snippet: These included strains that were resistant to erythromycin, tetracycline, vancomycin, and teicoplanin. table ft1 table-wrap mode="anchored" t5 caption a7 MIC ( μ g/mL) 1 10 13 16 83 84 vancomycin E. faecium ATCC BAA 2127 a 4 16 16 4 32 8 1 E. faecium 119-39A (Van S) b 4 4 8 4 16 8 0.5 E. faecium ATCC 700221(Van R) c 4 8 8 4 8 8 16 E. faecium C9 d 16 4 8 4 8 4 2 E. faecium C38 d 16 32 16 16 32 16 64 E. faecium C68 d , e 16 16 16 4 32 4 64 Open in a separate window a Resistant to copper, erythromycin, and tetracycline, and sensitive to vancomycin and teicoplanin. b Vancomycin-susceptible clinical isolate. c Isolated from human feces, vanA positive, resistant to vancomycin and teicoplanin. d Clinical strains isolated in Cleveland hospitals, gifts from Dr. Robert A. Bonomo. e Most prevalent VRE clinical strain from Cleveland hospitals.

Techniques:

Journal: Case Reports in Critical Care

Article Title: A Case Series of Persistent SARS-CoV-2 Infection in Immunocompromised Pediatric Patients

doi: 10.1155/2023/1699770

Figure Lengend Snippet: Summary of cases.

Article Snippet: Case 2 , 12-year-old , H/o ALL s/p bone marrow transplant , 4 weeks , Diffuse alveolar hemorrhage Pulmonary embolism , Remdesivir Hydrocortisone Tocilizumab Vancomycin Cefepime Amphotericin , Discharge home on room air.

Techniques: Transplantation Assay